University of Münster
Application Review Date
December 31, 2021
Open until filled
The Institute of Organismic and Molecular Evolution at the University of Mainz, Germany, invites applications for a Postdoc position in evolutionary single-cell genomics in the group of Evolutionary Plant Science and Biotic Interactions, headed by Prof. Shuqing Xu. Supported by other group members, the candidate will work on the evolution of gene functions and regulations at cellular level using use the state-of-the-art single-cell genomic tools. During the project, the candidate will mature his/her scientific skills and develop independence in project planning and management skills. The candidate is encouraged to apply for additional third-party funding to establish his/her own subgroup.
We are looking for a highly motivated researcher with a doctoral degree, or an equivalent thereof, in biology, evolutionary genetics, bioinformatics or computer science. The candidate is expected to design, conduct and organize the projects independently. Experience in analysing a large amount of next-generation sequencing data, in particular, single-cell sequencing and/or comparative genomics data, with a high degree of independence. A training background in bioinformatics, evolutionary genetics and single-cell sequencing is preferred. Applicants must demonstrate experience in statistics and genomics. Experience with molecular biology, epigenetics and computational modelling are a plus. Our group consists of people of various nationalities and teamwork is essential for all projects in the group. Therefore, excellent communication skills, as well as proficiency in spoken and written English, are expected. Good knowledge of German is a plus.
VIB-UGent Center for Inflammation Research
October 15, 2021
The Data Mining and Modeling for Biomedicine group (headed by Yvan Saeys) at the VIB Center for Inflammation Research and Ghent University is located in the historical city of Ghent, Belgium. The Saeys lab is at the forefront of computational method development in single-cell omics and has a longstanding collaboration with many wet labs in immunology, oncology, and plant biology. Recently, the lab has started a single-cell facility with advanced access to the newest single-cell multi-omics technologies (scRNA-seq, scATAC-seq, CITE-seq, and spatial proteomics and transcriptomics). A major focus of the lab is to model the dynamics of biological systems and characterize their underlying gene regulatory networks. To this end, the lab develops new computational machine learning methods to improve the current state-of-the-art.
The successful candidate will be responsible for developing novel methods (including trajectory inference and gene regulatory network inference) on single-cell omics data. The current position is part of a collaboration with BASF, a leading company in the plant biotechnology field, and the lab of Bert De Rybel at the VIB Center of Plant Systems Biology.
September 8, 2021
September 30, 2021
Institute of Biology Leiden, Leiden University
Plant diseases occur everywhere and are one of the major threats to our agriculture. Understanding how disease resistance works is one of the long-term missions in the newly established group led by Dr. Ding, and also the key to protecting plant health.
The PhD project will focus on investigating gene regulatory mechanisms involved in immunity activated by intracellular nucleotide-binding leucine-rich-repeat (NB-LRR) receptors (NLRs). This research will continue on the recent discovery that NLR-activated transcription in-part potentiated the cell-surface receptor-mediated immunity (Ngou et al. Nature 2021; Ding et al. JXB 2021).